Getting My ceesdekker.net To Work
Getting My ceesdekker.net To Work
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2009, discovery of a new phenotype for microorganisms in slim nanofluidic slits; and 1st detection of community protein buildings together DNA working with good-point out nanopores
Our team scientific tests bacterial mobile division and is also aiming to constitute a ‘base up biology’ in artificial cells that could autonomously divide. Our principal interest lies in mobile division, chromatin framework, and spatial Handle.
[Laughs] ‘It had been absolutely a terrific threat! At time, I was nicely aware that it could go Completely wrong Which I could develop into a lot less productive, but I just dismissed that. Curiosity has always been my strongest driving drive. And fortunately all of it worked out.’
Our perform was speedily adopted up by Other folks, most notably by Phaedon Avouris and colleagues at IBM, who in Oct 1998 revealed their results on transistors made out of solitary- and multi-walled carbon nanotubes in Utilized Physics Letters.
2012, discovery that nucleoid occlusion underlies the accuracy of bacterial mobile division; and first at any time research of your dynamics DNA supercoils and the discovery of supercoil hopping
The coiled-coil in the human Rad50 DNA repair protein incorporates distinct segments of increased adaptability
Since 2000 he moved to one-molecule biophysics and nanobiology, with investigation from DNA supercoiling reports of nucleosomes and DNA restore proteins to DNA translocation through nanopores. A short while ago his exploration has focused on studying mobile division with germs on chip, while his best curiosity is in the way of acknowledging synthetic cells.
Atomic drive microscopy shows that vaccinia topoisomerase IB generates filaments on DNA within a cooperative vogue
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Resolving the step size in condensin-driven DNA loop extrusion identifies ATP binding as the move-building system
An integrated microfluidic platform for quantifying drug permeation throughout biomimetic vesicle membranes
Mother nature Physics many thanks the anonymous reviewers for his or her contribution towards the peer evaluate of this function.
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2013, controlled shaping of Dwell bacterial cells into arbitrary shapes; and discovery of spontaneous fluctuations from the handedness of histone tetrasomes